Measurement of TLR-induced macrophage spreading by automated image analysis: differential role of Myd88 and MAPK in early and late responses

Measurement of TLR-induced macrophage spreading by automated image analysis: differential role of Myd88 and MAPK in early and late responses

Sensing of infectious danger by Toll-like receptors (TLR) on macrophages causes not only a reprogramming of the transcriptome but also changes in the cytoskeleton important for cell spreading and motility. Since manual determination of cell contact areas from fluorescence microscopy pictures is very...

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Bibliographic Details
Main Authors: Jens eWenzel, Christian eHeld, Ralf ePalmisano, Stefan eTeufel, Jean-Pierre eDavid, Thomas eWittenberg, Roland eLang
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-10-01
Series:Frontiers in Physiology
Subjects:
macrophage
TLR
image analysis
Spreading
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2011.00071/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2011.00071/full

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