Triphenylphosphine dibromide: A useful reagent for conversion of aldoximes into nitriles

A simple and convenient method for the synthesis of nitriles by dehydration of aldoximes has been developed using triphenylphosphine dibromide in acetonitrile at room temperature. A variety of aromatic and heteroaromatic aldoximes are converted into the corresponding nitriles in high yields.

Bibliographic Details
Main Authors: Fatemeh Darvish, Barahman Movassagh, Masoud Erfani
Format: Article
Language:English
Published: Elsevier 2015-11-01
Series:Arabian Journal of Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535212002249