Influence of Carrier (Polymer) Type and Drug-Carrier Ratio in the Development of Amorphous Dispersions for Solubility and Permeability Enhancement of Ritonavir
The influence of the ratio of Eudragit® L100-55 or Kolliphor® P188 on the solubility, dissolution, and permeability of ritonavir was studied with a goal of preparing solid dispersions (SDs) of ritonavir. SDs were formulated using solvent evaporation or lyophilization techniques, and evaluated for t...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
International Pharmaceutical Excipients Council
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| Series: | Journal of Excipients and Food Chemicals |
| Online Access: | http://jefc.scholasticahq.com/article/2579-influence-of-carrier-polymer-type-and-drug-carrier-ratio-in-the-development-of-amorphous-dispersions-for-solubility-and-permeability-enhancement-of-ritonavir.pdf |