Systems Modeling of Interactions between Mucosal Immunity and the Gut Microbiome during Clostridium difficile Infection.

Clostridium difficile infections are associated with the use of broad-spectrum antibiotics and result in an exuberant inflammatory response, leading to nosocomial diarrhea, colitis and even death. To better understand the dynamics of mucosal immunity during C. difficile infection from initiation thr...

Full description

Bibliographic Details
Main Authors: Andrew Leber, Monica Viladomiu, Raquel Hontecillas, Vida Abedi, Casandra Philipson, Stefan Hoops, Brad Howard, Josep Bassaganya-Riera
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4521955?pdf=render