Uncoupling Protein 2 Drives Myocardial Dysfunction in Murine Models of Septic Shock

Cardiac dysfunction is a major component of sepsis-induced multiorgan failure in critical care units. Uncoupling protein 2 (UCP2) involves immune response, regulation of oxidative stress, and maintenance of mitochondrial membrane potential as well as energy production. However, whether and how UCP2...

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Bibliographic Details
Main Authors: Rong Tang, Ping-ping Qi, Yan-song Liu, Liu Jia, Rui-jin Liu, Si-cong Wang, Chang-song Wang, Yang Gao, Hong-liang Wang, Kai-jiang Yu
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2019/9786101