Androgen signaling uses a writer and a reader of ADP-ribosylation to regulate protein complex assembly

Androgen signaling uses a writer and a reader of ADP-ribosylation to regulate protein complex assembly

Androgen receptor (AR) signaling is regulated by multiple post-translational modifications. Here, the authors identify the writer and reader enzymes for AR ADP-ribosylation and show how they modulate AR signaling output in prostate cancer cells.

Bibliographic Details
Main Authors: Chun-Song Yang, Kasey Jividen, Teddy Kamata, Natalia Dworak, Luke Oostdyk, Bartlomiej Remlein, Yasin Pourfarjam, In-Kwon Kim, Kang-Ping Du, Tarek Abbas, Nicholas E. Sherman, David Wotton, Bryce M. Paschal
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-23055-6

Internet

https://doi.org/10.1038/s41467-021-23055-6

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