Transmission Mechanism of Lewy Body-Like α-Synucleinopathies in Dopaminergic Neurons Derived from Human Induced Pluripotent Stem Cells

Grafting of cells in Parkinson's disease (PD) results in a prion-like infection, exhibiting a Lewy body-like pathology, caused by the recipient cells. The transmission mechanism of Lewy bodies is not completely understood. Therefore, a research idea with a novel experimental strategy is prop...

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Bibliographic Details
Main Author: Cheng Lin
Format: Article
Language:English
Published: Pensoft Publishers 2018-04-01
Series:Research Ideas and Outcomes
Subjects:
Online Access:https://riojournal.com/article/25423/