Red blood cells contain enzymatically active GPx4 whose abundance anticorrelates with hemolysis during blood bank storage

The antioxidant function of the phospholipid hydroperoxide glutathione peroxidase (GPx4) is vital for the homeostasis of many cell types, from neoplastic cells to normal erythroid precursors. However, some functional proteins in erythroid precursors are lost during the development of red blood cells...

Full description

Bibliographic Details
Main Authors: Jeffrey M. Stolwijk, Jonathan A. Stefely, Mike T. Veling, Thomas J. van ‘t Erve, Brett A. Wagner, Thomas J. Raife, Garry R. Buettner
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Redox Biology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231721002329