Breakpoint characterization of large deletions in <it>EXT1 </it>or <it>EXT2 </it>in 10 Multiple Osteochondromas families

Breakpoint characterization of large deletions in <it>EXT1 </it>or <it>EXT2 </it>in 10 Multiple Osteochondromas families

<p>Abstract</p> <p>Background</p> <p>Osteochondromas (cartilage-capped bone tumors) are by far the most commonly treated of all primary benign bone tumors (50%). In 15% of cases, these tumors occur in the context of a hereditary syndrome called multiple osteochondromas...

Full description

Bibliographic Details
Main Authors: Szuhai Karoly, Hogendoorn Pancras CW, Mees Kirsten, de Jong Danielle, Jennes Ivy, Wuyts Wim
Format: Article
Language:English
Published: BMC 2011-06-01
Series:BMC Medical Genetics
Subjects:
Multiple osteochondromas
<it>EXT1, EXT2</it>
deletion breakpoint
arrayCGH
NAHR
NHEJ
MMRDR
bone neoplasm
Online Access:http://www.biomedcentral.com/1471-2350/12/85

Internet

http://www.biomedcentral.com/1471-2350/12/85

Similar Items