A Microglia Sublineage Protects from Sex-Linked Anxiety Symptoms and Obsessive Compulsion

Summary: Aberrant microglia activity is associated with many neurological and psychiatric disorders, yet our knowledge about the pathological mechanisms is incomplete. Here, we describe a genetically defined microglia sublineage in mice which has the ability to suppress obsessive compulsion and anxi...

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Bibliographic Details
Main Authors: Dimitri Tränkner, Anne Boulet, Erik Peden, Richard Focht, Donn Van Deren, Mario Capecchi
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719312331