Cytotoxic, caspase-3 induction and in vivo hepatoprotective effects of phyllanthin, a major constituent of Phyllanthus niruri

The antiproliferative activity of phyllanthin (the major constituent in the decoction of Phyllanthus niruri L.) against human liver carcinoma HepG2 cells, the mechanism of cell death and the protective effect against carbon tetrachloride (CCl4)-induced hepatotoxicity in mice were investigated. Phyll...

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Bibliographic Details
Main Authors: Kheng Leong Ooi, Suh In Loh, Munavvar Abdul Sattar, Tengku Sifzizul Tengku Muhammad, Shaida Fariza Sulaiman
Format: Article
Language:English
Published: Elsevier 2015-04-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464615000365