Cladribine Combined with Low-Dose Cytarabine as Frontline Treatment for Unfit Elderly Acute Myeloid Leukemia Patients: Results from a Prospective Multicenter Study of Polish Adult Leukemia Group (PALG)

Cladribine Combined with Low-Dose Cytarabine as Frontline Treatment for Unfit Elderly Acute Myeloid Leukemia Patients: Results from a Prospective Multicenter Study of Polish Adult Leukemia Group (PALG)

Acute myeloid leukemia (AML) in older unfit patients is a therapeutic challenge for clinical hematologists. We evaluated the efficacy and safety of a novel low-intensity regimen consisting of low-dose cytarabine and cladribine (LD-AC+cladribine) in first-line treatment of elderly (≥60 years) AML pat...

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Bibliographic Details
Main Authors: Bożena Katarzyna Budziszewska, Aleksander Salomon-Perzyński, Katarzyna Pruszczyk, Joanna Barankiewicz, Agnieszka Pluta, Grzegorz Helbig, Anna Janowska, Marta Kuydowicz, Łukasz Bołkun, Jarosław Piszcz, Elżbieta Patkowska, Marzena Wątek, Piotr Małecki, Sylwia Kościołek-Zgódka, Edyta Cichocka, Grzegorz Charliński, Anna Irga-Staniukiewicz, Jan Maciej Zaucha, Agnieszka Piekarska, Tomasz Gromek, Marek Hus, Karol Wójcik, Małgorzata Raźny, Mariola Sędzimirska, Bartosz Puła, Sebastian Giebel, Sebastian Grosicki, Agnieszka Wierzbowska, Ewa Lech-Marańda
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
acute myeloid leukemia
elderly
unfit patients
cladribine
low-dose cytarabine
non-intensive therapy
Online Access:https://www.mdpi.com/2072-6694/13/16/4189

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https://www.mdpi.com/2072-6694/13/16/4189

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