Anti-Inflammatory Action of an Antimicrobial Model Peptide That Suppresses the TRIF-Dependent Signaling Pathway via Inhibition of Toll-Like Receptor 4 Endocytosis in Lipopolysaccharide-Stimulated Macrophages.

Anti-Inflammatory Action of an Antimicrobial Model Peptide That Suppresses the TRIF-Dependent Signaling Pathway via Inhibition of Toll-Like Receptor 4 Endocytosis in Lipopolysaccharide-Stimulated Macrophages.

Antimicrobial peptides (AMPs), also called host defense peptides, particularly those with amphipathic helical structures, are emerging as target molecules for therapeutic development due to their immunomodulatory properties. Although the antimicrobial activity of AMPs is known to be exerted primaril...

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Bibliographic Details
Main Authors: Do-Wan Shim, Kang-Hyuck Heo, Young-Kyu Kim, Eun-Jeong Sim, Tae-Bong Kang, Jae-Wan Choi, Dae-Won Sim, Sun-Hee Cheong, Seung-Hong Lee, Jeong-Kyu Bang, Hyung-Sik Won, Kwang-Ho Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4446091?pdf=render

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http://europepmc.org/articles/PMC4446091?pdf=render

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