Central tetrahydrobiopterin concentration in neurodevelopmental disorders

Tetrahydrobiopterin (BH4) is a naturally occurring cofactor essential for critical metabolic pathways. Studies suggest that BH4 supplementation may ameliorate autism symptoms; the biological mechanism for such an effect is unknown. To help understand the relation between central BH4 concentratio...

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Bibliographic Details
Main Author: Richard E Frye
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-07-01
Series:Frontiers in Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2010.00052/full