Adjuvants and the vaccine response to the DS-Cav1-stabilized fusion glycoprotein of respiratory syncytial virus.

Appropriate adjuvant selection may be essential to optimize the potency and to tailor the immune response of subunit vaccines. To induce protective responses against respiratory syncytial virus (RSV)-a highly prevalent childhood pathogen without a licensed vaccine-we previously engineered a pre-fusi...

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Bibliographic Details
Main Authors: Mallika Sastry, Baoshan Zhang, Man Chen, M Gordon Joyce, Wing-Pui Kong, Gwo-Yu Chuang, Kiyoon Ko, Azad Kumar, Chiara Silacci, Michelle Thom, Andres M Salazar, Davide Corti, Antonio Lanzavecchia, Geraldine Taylor, John R Mascola, Barney S Graham, Peter D Kwong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0186854