Circulating trophoblast cell clusters for early detection of placenta accreta spectrum disorders

Placenta accreta spectrum (PAS) is a high-risk obstetrical complication associated with significant morbidity and mortality. Here the authors discover a uniquely high prevalence of circulating trophoblasts clusters in PAS and explore their diagnostic potential to augment current diagnostic modalitie...

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Bibliographic Details
Main Authors: Yalda Afshar, Jiantong Dong, Pan Zhao, Lei Li, Shan Wang, Ryan Y. Zhang, Ceng Zhang, Ophelia Yin, Christina S. Han, Brett D. Einerson, Tania L. Gonzalez, Huirong Zhang, Anqi Zhou, Zhuo Yang, Shih-Jie Chou, Na Sun, Ju Cheng, Henan Zhu, Jing Wang, Tiffany X. Zhang, Yi-Te Lee, Jasmine J. Wang, Pai-Chi Teng, Peng Yang, Dongping Qi, Meiping Zhao, Myung-Shin Sim, Ruilian Zhe, Jeffrey D. Goldstein, John Williams, Xietong Wang, Qingying Zhang, Lawrence D. Platt, Chang Zou, Margareta D. Pisarska, Hsian-Rong Tseng, Yazhen Zhu
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-24627-2