The Influence of Long-term Diabetes Mellitus on Pain Response in Mice: In Vivo Models of Painful Diabetic Neuropathy (PDN)

ABSTRACT Painful diabetic neuropathy (PDN) is a complication of long-term Diabetes Mellitus (DM) characterized by hyperalgesia and allodynia. In streptozotocin (STZ)-induced diabetic mice, higher dose of STZ and lengthen hiperglycemic condition results in better model of PDN. However, higher dose of...

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Bibliographic Details
Main Authors: Fifteen Aprila Fajrin, R Susilowati, A Nurrochmad, AE Nugroho
Format: Article
Language:English
Published: Universitas Gadjah Mada 2017-03-01
Series:Journal of the Medical Sciences
Online Access:https://jurnal.ugm.ac.id/bik/article/view/18951