Evolution of cagA oncogene of Helicobacter pylori through recombination.

Helicobacter pylori is a gastric pathogen that infects half the human population and causes gastritis, ulcers, and cancer. The cagA gene product is a major virulence factor associated with gastric cancer. It is injected into epithelial cells, undergoes phosphorylation by host cell kinases, and pertu...

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Bibliographic Details
Main Authors: Yoshikazu Furuta, Koji Yahara, Masanori Hatakeyama, Ichizo Kobayashi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3154945?pdf=render