COX-2-765G>C polymorphism increases the risk of cancer: a meta-analysis.

BACKGROUND: Chronic inflammation has been regarded as an important mechanism in carcinogenesis. Inflammation-associated genetic variants have been highly associated with cancer risk. Polymorphisms in the gene cyclooxygenase-2 (COX-2), a pro-inflammation factor, have been suggested to alter the risk...

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Bibliographic Details
Main Authors: Xiao-feng Wang, Ming-zhu Huang, Xiao-wei Zhang, Rui-xi Hua, Wei-jian Guo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3762903?pdf=render