Reducing Lung ATP Levels and Alleviating Asthmatic Airway Inflammation through Adeno-Associated Viral Vector-Mediated CD39 Expression

Reducing Lung ATP Levels and Alleviating Asthmatic Airway Inflammation through Adeno-Associated Viral Vector-Mediated CD39 Expression

Asthma is a chronic respiratory inflammatory disease. Patients usually suffer long-term symptoms and high medical expenses. Extracellular ATP (eATP) has been identified as a danger signal in innate immunity and serves as a potent inflammatory mediator for asthma. Hydrolyzing eATP in lungs might be a...

Full description

Bibliographic Details
Main Authors: Yung-An Huang, Jeng-Chang Chen, Chih-Ching Wu, Chia-Wei Hsu, Albert Min-Shan Ko, Li-Chen Chen, Ming-Ling Kuo
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Biomedicines
Subjects:
apyrase
adeno-associated viral vector
airway hyperresponsiveness
cytokine
regulatory T cells
Online Access:https://www.mdpi.com/2227-9059/9/6/656

Internet

https://www.mdpi.com/2227-9059/9/6/656

Similar Items