Basic evidence for class A G-protein-coupled receptor heteromerization

Cell membrane receptors rarely work on isolation, often they form oligomeric complexes with other receptor molecules and they may directly interact with different proteins of the signal transduction machinery. For a variety of reasons, rhodopsin-like class A G-protein-coupled receptors (GPCRs) seem...

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Bibliographic Details
Main Authors: Rafael eFranco, Eva eMartínez-Pinilla, Jose L Lanciego, Gema eNavarro
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00076/full