Local electromechanical alterations determine the left ventricle rotational dynamics in CRT-eligible heart failure patients

Abstract Left ventricle, LV wringing wall motion relies on physiological muscle fiber orientation, fibrotic status, and electromechanics (EM). The loss of proper EM activation can lead to rigid-body-type (RBT) LV rotation, which is associated with advanced heart failure (HF) and challenges in resync...

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Bibliographic Details
Main Authors: Tomasz Jadczyk, Radoslaw Kurzelowski, Krzysztof S. Golba, Jacek Wilczek, Guido Caluori, Francesco Maffessanti, Jolanta Biernat, Katarzyna Gruszczynska, Magdalena Cybulska, Maximilian Y. Emmert, Zofia Parma, Kamil Baranski, Mieczyslaw Dutka, Barbara Kalanska-Lukasik, Zdenek Starek, Wojciech Wojakowski
Format: Article
Language:English
Published: Nature Publishing Group 2021-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-82793-1