Curation of the Mammalian Palmitoylome Indicates a Pivotal Role for Palmitoylation in Diseases and Disorders of the Nervous System and Cancers.

Curation of the Mammalian Palmitoylome Indicates a Pivotal Role for Palmitoylation in Diseases and Disorders of the Nervous System and Cancers.

Palmitoylation involves the reversible posttranslational addition of palmitate to cysteines and promotes membrane binding and subcellular localization. Recent advancements in the detection and identification of palmitoylated proteins have led to multiple palmitoylation proteomics studies but these d...

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Bibliographic Details
Main Authors: Shaun S Sanders, Dale D O Martin, Stefanie L Butland, Mathieu Lavallée-Adam, Diego Calzolari, Chris Kay, John R Yates, Michael R Hayden
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-08-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1004405

Internet

https://doi.org/10.1371/journal.pcbi.1004405

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