CHROMATOGATE: A TOOL FOR DETECTING BASE MIS-CALLS IN MULTIPLE SEQUENCE ALIGNMENTS BY SEMI-AUTOMATIC CHROMATOGRAM INSPECTION

CHROMATOGATE: A TOOL FOR DETECTING BASE MIS-CALLS IN MULTIPLE SEQUENCE ALIGNMENTS BY SEMI-AUTOMATIC CHROMATOGRAM INSPECTION

Automated DNA sequencers generate chromatograms that contain raw sequencing data. They also generate data that translates the chromatograms into molecular sequences of A, C, G, T, or N (undetermined) characters. Since chromatogram translation programs frequently introduce errors, a manual inspection...

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Bibliographic Details
Main Authors: Nikolaos Alachiotis, Emmanouella Vogiatzi, Pavlos Pavlidis, Alexandros Stamatakis
Format: Article
Language:English
Published: Elsevier 2013-03-01
Series:Computational and Structural Biotechnology Journal
Subjects:
chromatograms
software
mis-calls
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037014601100

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http://www.sciencedirect.com/science/article/pii/S2001037014601100

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