CFTR targeted therapies: recent advances in cystic fibrosis and possibilities in other diseases of the airways
Cystic fibrosis transmembrane conductance regulator (CFTR) is an ion transporter that regulates mucus hydration, viscosity and acidity of the airway epithelial surface. Genetic defects in CFTR impair regulation of mucus homeostasis, causing severe defects of mucociliary clearance as seen in cystic f...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
European Respiratory Society
2020-06-01
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| Series: | European Respiratory Review |
| Online Access: | http://err.ersjournals.com/content/29/156/190068.full |