CFTR targeted therapies: recent advances in cystic fibrosis and possibilities in other diseases of the airways

CFTR targeted therapies: recent advances in cystic fibrosis and possibilities in other diseases of the airways

Cystic fibrosis transmembrane conductance regulator (CFTR) is an ion transporter that regulates mucus hydration, viscosity and acidity of the airway epithelial surface. Genetic defects in CFTR impair regulation of mucus homeostasis, causing severe defects of mucociliary clearance as seen in cystic f...

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Bibliographic Details
Main Authors:	Sheylan D. Patel, Taylor R. Bono, Steven M. Rowe, George M. Solomon
Format:	Article
Language:	English
Published:	European Respiratory Society 2020-06-01
Series:	European Respiratory Review
Online Access:	http://err.ersjournals.com/content/29/156/190068.full

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