Spinal fMRI reveals decreased descending inhibition during secondary mechanical hyperalgesia.

Mechanical hyperalgesia is one distressing symptom of neuropathic pain which is explained by central sensitization of the nociceptive system. This sensitization can be induced experimentally with the heat/capsaicin sensitization model. The aim was to investigate and compare spinal and supraspinal ac...

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Bibliographic Details
Main Authors: Torge Rempe, Stephan Wolff, Christian Riedel, Ralf Baron, Patrick W Stroman, Olav Jansen, Janne Gierthmühlen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4221460?pdf=render