Roux-en-Y gastric bypass surgery is effective in fibroblast growth factor-21 deficient mice

Objective: The mechanisms by which bariatric surgeries so effectively and lastingly reduce body weight and normalize metabolic dysfunction are not well understood. Fibroblast growth fator-21 (FGF21) is a key regulator of metabolism and is currently considered for treatment of obesity. Although eleva...

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Bibliographic Details
Main Authors: Christopher D. Morrison, Zheng Hao, Michael B. Mumphrey, R. Leigh Townsend, Heike Münzberg, Jianping Ye, Hans-Rudolf Berthoud
Format: Article
Language:English
Published: Elsevier 2016-10-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877816301193