A Rare Missense Mutation and a Polymorphism with High Frequency in LDLR Gene among Iranian Patients with Familial Hypercholesterolemia

A Rare Missense Mutation and a Polymorphism with High Frequency in LDLR Gene among Iranian Patients with Familial Hypercholesterolemia

Background: Familial hypercholesterolemia (FH) is a disorder that is inherited by autosomal dominant pattern. The main cause of FH disease is the occurrence of mutations in low-density lipoprotein receptor (LDLR) gene sequence, as well as apolipoprotein B and proprotein convertase subtilisin/kexin t...

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Bibliographic Details
Main Authors: Masoud Tajamolian, Parisa Kolahdouz, Parvaneh Nikpour, Seyed Khalil Forouzannia, Mohammad Hasan Sheikhha, Ehsan Farashahi Yazd
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Advanced Biomedical Research
Subjects:
Familial hypercholesterolemia
high-resolution melting
Iran
low-density lipoprotein receptor
missense mutation
Online Access:http://www.advbiores.net/article.asp?issn=2277-9175;year=2018;volume=7;issue=1;spage=37;epage=37;aulast=Tajamolian

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http://www.advbiores.net/article.asp?issn=2277-9175;year=2018;volume=7;issue=1;spage=37;epage=37;aulast=Tajamolian

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