Differences in pathological changes between two rat models of severe traumatic brain injury

Differences in pathological changes between two rat models of severe traumatic brain injury

The rat high-impact free weight drop model mimics the diffuse axonal injury caused by severe traumatic brain injury in humans, while severe controlled cortical impact can produce a severe traumatic brain injury model using precise strike parameters. In this study, we compare the pathological mechani...

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Bibliographic Details
Main Authors: Yi-Ming Song, Yu Qian, Wan-Qiang Su, Xuan-Hui Liu, Jin-Hao Huang, Zhi-Tao Gong, Hong-Liang Luo, Chuang Gao, Rong-Cai Jiang
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; severe traumatic brain injury; animal model comparison; free weight drop; controlled cortical impact; neurological impairment; neuroinflammation; blood-brain barrier damage; neuronal apoptosis; diffuse axonal injury; brainstem injury; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=10;spage=1796;epage=1804;aulast=Song

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2019;volume=14;issue=10;spage=1796;epage=1804;aulast=Song

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