The Impact of Dose Rate on DNA Double-Strand Break Formation and Repair in Human Lymphocytes Exposed to Fast Neutron Irradiation

The Impact of Dose Rate on DNA Double-Strand Break Formation and Repair in Human Lymphocytes Exposed to Fast Neutron Irradiation

The lack of information on how biological systems respond to low-dose and low dose-rate exposures makes it difficult to accurately assess the carcinogenic risks. This is of critical importance to space radiation, which remains a serious concern for long-term manned space exploration. In this study,...

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Bibliographic Details
Main Authors: Shankari Nair, Monique Engelbrecht, Xanthene Miles, Roya Ndimba, Randall Fisher, Peter du Plessis, Julie Bolcaen, Jaime Nieto-Camero, Evan de Kock, Charlot Vandevoorde
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:International Journal of Molecular Sciences
Subjects:
dna double-strand breaks
γ-h2ax
neutrons
low dose rate
high dose rate
lymphocytes
Online Access:https://www.mdpi.com/1422-0067/20/21/5350

Internet

https://www.mdpi.com/1422-0067/20/21/5350

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