Variability in porcine microRNA genes and its association with mRNA expression and lipid phenotypes

Abstract Background Mature microRNAs (miRNAs) play an important role in repressing the expression of a wide range of mRNAs. The presence of polymorphic sites in miRNA genes and their corresponding 3′UTR binding sites can disrupt canonical conserved miRNA–mRNA pairings, and thus modify gene expressio...

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Bibliographic Details
Main Authors: Emilio Mármol-Sánchez, María Gracia Luigi-Sierra, Anna Castelló, Dailu Guan, Raquel Quintanilla, Raul Tonda, Marcel Amills
Format: Article
Language:deu
Published: BMC 2021-05-01
Series:Genetics Selection Evolution
Online Access:https://doi.org/10.1186/s12711-021-00632-3