Cocaine-Induced Synaptic Redistribution of NMDARs in Striatal Neurons Alters NMDAR-Dependent Signal Transduction

Cocaine-Induced Synaptic Redistribution of NMDARs in Striatal Neurons Alters NMDAR-Dependent Signal Transduction

The consequence of repeated cocaine exposure and prolonged abstinence on glutamate receptor expression in the nucleus accumbens has been extensively studied. However, the early effects of cocaine on NMDAR signaling remain unknown. NMDAR signaling depends on the subunit composition, subcellular local...

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Bibliographic Details
Main Authors: Ilse Delint-Ramirez, Amir Segev, Asha Pavuluri, David W. Self, Saïd Kourrich
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Neuroscience
Subjects:
NMDA receptor
ERK signaling
cocaine
postsynaptic density
extrasynaptic
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00698/full

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https://www.frontiersin.org/article/10.3389/fnins.2020.00698/full

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