Short tandem repeat near hypoxia response element (HRE) instead of HRE genetic variants in promoter calcitonin receptor-like receptor (CRLR) gene as risk factor in severe preeclampsia: a preliminary study

Abstract Objective Calcitonin receptor-like receptor (CRLR) regulates vasoconstriction and dilatation; the expression increases during hypoxia via activation of hypoxia response element (HRE) in CRLR gene promoter region. Variant in HRE, as well short tandem repeat (STR) variants near HRE in CRLR al...

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Bibliographic Details
Main Authors: Herlambang, Amelia Dwi Fitri, Ahmad Syauqy, Yuwono, Anggelia Puspasari, Rina Nofri Enis, Ahmad Faried
Format: Article
Language:English
Published: BMC 2021-01-01
Series:BMC Research Notes
Subjects:
HRE
Online Access:https://doi.org/10.1186/s13104-020-05437-z