NAMPT and NAPRT, Key Enzymes in NAD Salvage Synthesis Pathway, Are of Negative Prognostic Value in Colorectal Cancer

NAMPT and NAPRT, Key Enzymes in NAD Salvage Synthesis Pathway, Are of Negative Prognostic Value in Colorectal Cancer

Nicotinamide adenine dinucleotide (NAD) is a profoundly important cofactor in redox reactions. Nicotinamide phosphoribosyltransferase (NAMPT) and nicotinate phosphoribosyltransferase (NAPRT) are key enzymes for NAD salvage biosynthesis pathway, which reciprocally synthesize NAD to supply the main so...

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Bibliographic Details
Main Authors: Xiao-qin Li, Jing Lei, Lin-hong Mao, Qing-liang Wang, Feng Xu, Tao Ran, Zhi-hang Zhou, Song He
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Oncology
Subjects:
colorectal cancer
NAMPT
NAPRT
NAD
prognosis
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00736/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2019.00736/full

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