Characterization of Pb51 in Plasmodium berghei as a malaria vaccine candidate targeting both asexual erythrocytic proliferation and transmission

Characterization of Pb51 in Plasmodium berghei as a malaria vaccine candidate targeting both asexual erythrocytic proliferation and transmission

Abstract Background A vaccine that targets multiple developmental stages of malaria parasites would be an effective tool for malaria control and elimination. Methods A conserved gene in Plasmodium, the Plasmodium berghei gene (PBANKA_020570) encoding a 51 kDa protein (pb51 gene), was identified thro...

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Bibliographic Details
Main Authors: Jian Wang, Wenqi Zheng, Fei Liu, Yaru Wang, Yiwen He, Li Zheng, Qi Fan, Enjie Luo, Yaming Cao, Liwang Cui
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Malaria Journal
Subjects:
Plasmodium berghei
Pb51
Vaccine candidate
Asexual blood stage
Sexual stage
Transmission-blocking
Online Access:http://link.springer.com/article/10.1186/s12936-017-2107-2

Internet

http://link.springer.com/article/10.1186/s12936-017-2107-2

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