Extended Freeze-Dried BCG Instructed pDCs Induce Suppressive Tregs and Dampen EAE

Extended Freeze-Dried BCG Instructed pDCs Induce Suppressive Tregs and Dampen EAE

Several clinical observations have shown that Bacillus Calmette-Guérin (BCG) vaccine has beneficial impact on patients suffering from different chronic inflammatory diseases. Here we evaluated whether BCG inactivated by Extended Freeze-Drying (EFD) which circumvents all the side effects linked to th...

Full description

Bibliographic Details
Main Authors: Carla Lippens, Laure Garnier, Pierre-Marie Guyonvarc'h, Marie-Laure Santiago-Raber, Stéphanie Hugues
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Immunology
Subjects:
experimental autoimmue encephalomyelitis model
plasmacytoid DCs (pDCs)
regulatory T (Treg) cells
tolerance
BCG–Bacille Calmette-Guérin vaccine
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02777/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02777/full

Similar Items