A case of EGFR mutant lung adenocarcinoma that acquired resistance to EGFR-tyrosine kinase inhibitors with MET amplification and epithelial-to-mesenchymal transition

Seigo Miyoshi,1 Takahide Kato,1 Hitoshi Katayama,1 Ryoji Ito,1 Yosuke Mizuno,2 Takafumi Okura,1 Jitsuo Higaki1 1Department of Cardiology, Pulmonology, Hypertension and Nephrology, Ehime University Graduate School of Medicine, Ehime, Japan; 2Department of Molecular Pathology, Ehime Univers...

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Bibliographic Details
Main Authors: Miyoshi S, Kato T, Katayama H, Ito R, Mizuno Y, Okura T, Higaki J
Format: Article
Language:English
Published: Dove Medical Press 2015-04-01
Series:OncoTargets and Therapy
Online Access:http://www.dovepress.com/a-case-of-egfr-mutant-lung-adenocarcinoma-that-acquired-resistance-to--peer-reviewed-article-OTT