2A-DUB/Mysm1 Regulates Epidermal Development in Part by Suppressing p53-Mediated Programs

2A-DUB/Mysm1 Regulates Epidermal Development in Part by Suppressing p53-Mediated Programs

Development and homeostasis of the epidermis are governed by a complex network of sequence-specific transcription factors and epigenetic modifiers cooperatively regulating the subtle balance of progenitor cell self-renewal and terminal differentiation. To investigate the role of histone H2A deubiqui...

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Bibliographic Details
Main Authors: Christina Wilms, Ioanna Krikki, Adelheid Hainzl, Sonja Kilo, Marius Alupei, Evgenia Makrantonaki, Maximilian Wagner, Carsten M. Kroeger, Titus Josef Brinker, Martina Gatzka
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:International Journal of Molecular Sciences
Subjects:
apoptosis
DUB
epidermal barrier
epidermal stem cell
epigenetics
histone modification
Mysm1
p53
p63
skin
Online Access:http://www.mdpi.com/1422-0067/19/3/687

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http://www.mdpi.com/1422-0067/19/3/687

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