Three-Component Access to Functionalized Spiropyrrolidine Heterocyclic Scaffolds and Their Cholinesterase Inhibitory Activity

A novel <i>one-pot</i> [3+2]-cycloaddition reaction of <i>(E)-</i>3-arylidene-1-phenyl-succinimides, cyclic 1,2-diketones (isatin, 5-chloro-isatin and acenaphtenequinone), and diverse <i>α-</i>aminoacids such as 2-phenylglycine or sarcosine is reported. The reacti...

Full description

Bibliographic Details
Main Authors: Sarra Boudriga, Saoussen Haddad, Vikneswaran Murugaiyah, Moheddine Askri, Michael Knorr, Carsten Strohmann, Christopher Golz
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/8/1963