Revealing Dynamic Mechanisms of Cell Fate Decisions From Single-Cell Transcriptomic Data
Cell fate decisions play a pivotal role in development, but technologies for dissecting them are limited. We developed a multifunction new method, Topographer, to construct a “quantitative” Waddington’s landscape of single-cell transcriptomic data. This method is able to identify complex cell-state...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2019-12-01
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| Series: | Frontiers in Genetics |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/article/10.3389/fgene.2019.01280/full |