Pharmacokinetics of meropenem in burn patients with infections caused by Gram-negative bacteria: Are we getting close to the right treatment?

Pharmacokinetics of meropenem in burn patients with infections caused by Gram-negative bacteria: Are we getting close to the right treatment?

Objectives: Infections caused by multidrug-resistant Gram-negative bacteria are associated with high mortality. A relevant concern is the efficacy of antibiotic therapy in burn patients in whom pathophysiological changes strongly influence pharmacokinetic (PK) parameters. This study aimed to describ...

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Bibliographic Details
Main Authors: Silvia Corcione, Antonio D’Avolio, Riccardo Corgiat Loia, Anna Pensa, Francesco Vladimiro Segala, Amedeo De Nicolò, Giovanna Fatiguso, Mariarosa Romeo, Giovanni Di Perri, Maurizio Stella, Francesco Giuseppe De Rosa
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
Burn
Meropenem
Pharmacokinetics
Pharmacodynamics
Multidrug-resistant
Infection
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716519301559

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http://www.sciencedirect.com/science/article/pii/S2213716519301559

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