Microglial Progranulin: Involvement in Alzheimer’s Disease and Neurodegenerative Diseases

Microglial Progranulin: Involvement in Alzheimer’s Disease and Neurodegenerative Diseases

Neurodegenerative diseases such as Alzheimer’s disease have proven resistant to new treatments. The complexity of neurodegenerative disease mechanisms can be highlighted by accumulating evidence for a role for a growth factor, progranulin (PGRN). PGRN is a glycoprotein encoded by the GRN/G...

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Bibliographic Details
Main Authors: Anarmaa Mendsaikhan, Ikuo Tooyama, Douglas G. Walker
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cells
Subjects:
neuroinflammation
growth factor
anti-inflammatory
mutation
amyloid
neurodegeneration
Online Access:http://www.mdpi.com/2073-4409/8/3/230

Internet

http://www.mdpi.com/2073-4409/8/3/230

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