The missing story behind Genome Wide Association Studies: single nucleotide polymorphisms in gene deserts have a story to tell

Genome wide association studies are central to the evolution of personalized medicine. However, the propensity for SNPs to fall outside of genes means that understanding how these polymorphisms alter cellular function requires an expanded view of human genetics. Integrating the study of genome struc...

Full description

Bibliographic Details
Main Authors: William Stewart Schierding, Wayne S. Cutfield, Justin Martin O'Sullivan
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-02-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00039/full