Mesenchymal Stromal Cell Derived Extracellular Vesicles Reduce Hypoxia-Ischaemia Induced Perinatal Brain Injury

Mesenchymal Stromal Cell Derived Extracellular Vesicles Reduce Hypoxia-Ischaemia Induced Perinatal Brain Injury

BackgroundNeonatal hypoxic-ischemic (HI) insult is a leading cause of disability and death in newborns, with therapeutic hypothermia being the only currently available clinical intervention. Thus there is a great need for adjunct and novel treatments for enhanced or alternative post-HI neuroprotecti...

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Bibliographic Details
Main Authors: Claudia Sisa, Sharad Kholia, Jordan Naylor, Maria Beatriz Herrera Sanchez, Stefania Bruno, Maria Chiara Deregibus, Giovanni Camussi, Jameel M. Inal, Sigrun Lange, Mariya Hristova
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Physiology
Subjects:
hypoxia
ischaemia
extracellular vesicles
mesenchymal stromal/stem cells
microglia
neuroprotection
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00282/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.00282/full

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