Naltrexone blockade of OGFr enhances cutaneous wound closure in diabetic rats

Aims: Non-healing wounds are a major complication for the 27 million individuals in the United States with diagnosed diabetes. This study investigated the efficacy of a novel formulation to treat diabetic foot ulcers by targeting an underlying pathophysiology of diabetes. Main methods: The proprieta...

Full description

Bibliographic Details
Main Authors: Patricia J. McLaughlin, Joseph W. Sassani, Indira Purushothaman, Ian S. Zagon
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Medicine in Drug Discovery
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2590098621000191