Activation of NF-kB pathway by virus infection requires Rb expression.

The retinoblastoma protein Rb is a tumor suppressor involved in cell cycle control, differentiation, and inhibition of oncogenic transformation. Besides these roles, additional functions in the control of immune response have been suggested. In the present study we investigated the consequences of l...

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Bibliographic Details
Main Authors: Maria A Garcia, Pedro Gallego, Michela Campagna, José González-Santamaría, Gloria Martínez, Laura Marcos-Villar, Anxo Vidal, Mariano Esteban, Carmen Rivas
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-07-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2713421?pdf=render