PIWI-interacting RNA sequencing profiles in maternal plasma-derived exosomes reveal novel non-invasive prenatal biomarkers for the early diagnosis of nonsyndromic cleft lip and palate

PIWI-interacting RNA sequencing profiles in maternal plasma-derived exosomes reveal novel non-invasive prenatal biomarkers for the early diagnosis of nonsyndromic cleft lip and palate

Background: Congenital malformations are common birth defects with high neonatal morbidity and mortality. It is essential to find simpler and more efficient biomarkers for early prenatal diagnosis. Therefore, we investigated PIWI-interacting RNAs (piRNAs) as potential prenatal biomarkers in plasma-d...

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Bibliographic Details
Main Authors: Shanshan Jia, Qiang Zhang, Yu Wang, Yanfu Wang, Dan Liu, Yiwen He, Xiaowei Wei, Hui Gu, Wei Ma, Wenting Luo, Zhengwei Yuan
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:EBioMedicine
Subjects:
Biomarker
Congenital heart defect
Neural tube defect
Nonsyndromic cleft lip and palate
PIWI-interacting RNA
Prenatal diagnosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396421000463

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http://www.sciencedirect.com/science/article/pii/S2352396421000463

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