Molecular dating and viral load growth rates suggested that the eclipse phase lasted about a week in HIV-1 infected adults in East Africa and Thailand.

Most HIV-1 infected individuals do not know their infection dates. Precise infection timing is crucial information for studies that document transmission networks or drug levels at infection. To improve infection timing, we used the prospective RV217 cohort where the window when plasma viremia becom...

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Main Authors: Morgane Rolland, Sodsai Tovanabutra, Bethany Dearlove, Yifan Li, Christopher L Owen, Eric Lewitus, Eric Sanders-Buell, Meera Bose, AnneMarie O'Sullivan, Raabya Rossenkhan, Jan Phillipus Lourens Labuschagne, Paul T Edlefsen, Daniel B Reeves, Gustavo Kijak, Shana Miller, Kultida Poltavee, Jenica Lee, Lydia Bonar, Elizabeth Harbolick, Bahar Ahani, Phuc Pham, Hannah Kibuuka, Lucas Maganga, Sorachai Nitayaphan, Fred K Sawe, Leigh Anne Eller, Robert Gramzinski, Jerome H Kim, Nelson L Michael, Merlin L Robb, RV217 Study Team
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-02-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008179