Lack of the Transient Receptor Potential Vanilloid 1 Shifts Cannabinoid-Dependent Excitatory Synaptic Plasticity in the Dentate Gyrus of the Mouse Brain Hippocampus

Lack of the Transient Receptor Potential Vanilloid 1 Shifts Cannabinoid-Dependent Excitatory Synaptic Plasticity in the Dentate Gyrus of the Mouse Brain Hippocampus

The transient receptor potential vanilloid 1 (TRPV1) participates in synaptic functions in the brain. In the dentate gyrus, post-synaptic TRPV1 in the granule cell (GC) dendritic spines mediates a type of long-term depression (LTD) of the excitatory medial perforant path (MPP) synapses independent o...

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Bibliographic Details
Main Authors: Jon Egaña-Huguet, Miquel Saumell-Esnaola, Svein Achicallende, Edgar Soria-Gomez, Itziar Bonilla-Del Río, Gontzal García del Caño, Sergio Barrondo, Joan Sallés, Inmaculada Gerrikagoitia, Nagore Puente, Izaskun Elezgarai, Pedro Grandes
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Neuroanatomy
Subjects:
endovanilloid system
CB1 receptor
excitatory synapses
long-term potentiation
G proteins
Online Access:https://www.frontiersin.org/articles/10.3389/fnana.2021.701573/full

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https://www.frontiersin.org/articles/10.3389/fnana.2021.701573/full

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